Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Membrane attack complex component/perforin/complement C9
- Thrombospondin type-1 (TSP1) repeat
- Low-density lipoprotein (LDL) receptor class A repeat
- Thrombospondin type-1 (TSP1) repeat superfamily
- Membrane attack complex component/perforin (MACPF) domain
- Sushi/SCR/CCP domain
- LDL receptor-like superfamily
- Membrane attack complex component/perforin domain, conserved site
31 more domains
Structure analysis Details
Assembly composition:
hetero nonamer (preferred)
Assembly name:
C5b6 complement complex (preferred)
PDBe Complex ID:
PDB-CPX-133865 (preferred)
Entry contents:
8 distinct polypeptide molecules
Macromolecules (8 distinct):
CD59 glycoprotein
Molecule details ›
Chain: G
Length: 128 amino acids
Theoretical weight: 14.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: u-PAR/Ly-6 domain
Length: 128 amino acids
Theoretical weight: 14.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
P13987 (Residues: 1-128; Coverage: 100%)
Sequence domains: u-PAR/Ly-6 domain
Complement component C8 beta chain
Molecule details ›
Chain: D
Length: 591 amino acids
Theoretical weight: 67.14 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains:
Length: 591 amino acids
Theoretical weight: 67.14 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P07358 (Residues: 1-591; Coverage: 100%)
Sequence domains:
Complement component C8 gamma chain
Complement component C8 alpha chain
Complement C5
Complement component C7
Complement component C6
Complement component C9
