› 8b6x

Solution NMR

NMR assignment and structure of a peptide derived from the membrane proximal external region of HIV-1 gp41 in DPC micelles

Released:
DOI: 10.2210/pdb8b6x/pdb
PDB entry 8b6x coloured by chain, ensemble of 20 models, front view.
PDB entry 8b6x coloured by chain, ensemble of 20 models, side view.
PDB entry 8b6x coloured by chain, ensemble of 20 models, top view.
Source organism: Human immunodeficiency virus 1
Primary publication:
Molecular recognition of a membrane-anchored HIV-1 pan-neutralizing epitope.
Torralba J, de la Arada I, Partida-Hanon A, Rujas E, Arribas M, Insausti S, Valotteau C, Valle J, Andreu D, Caaveiro JMM, Jiménez MA, Apellániz B, Redondo-Morata L, Nieva JL
OpenAccess logo Commun Biol 5 1265 (2022)
PMID: 36400835

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-269138 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transmembrane protein gp41 Chain: A
Molecule details ›
Chain: A
Length: 25 amino acids
Theoretical weight: 3.22 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Not provided
UniProt:
  • Canonical: A0A2P1GRC5 (Residues: 675-694; Coverage: 2%)
Gene name: env

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this NMR entry.
Chemical shift assignment: 75%
Refinement method: torsion angle dynamics
Expression system: Not provided

Quick links

Citations

1 citations in other articles

African Swine Fever Virus Gene B117L Encodes a Small Protein Endowed with Low-pH-Dependent Membrane Permeabilizing Activity.
Gladue et al. (2023)

1 mention without citation

Molecular recognition of a membrane-anchored HIV-1 pan-neutralizing epitope.
Torralba et al. (2022)