Function and Biology Details
Reactions catalysed:
ATP + H(2)O = ADP + phosphate
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero icosamer (preferred)
Assembly name:
GINS complex and DNA (preferred)
PDBe Complex ID:
PDB-CPX-224766 (preferred)
Entry contents:
18 distinct polypeptide molecules
2 distinct DNA molecules
2 distinct DNA molecules
Macromolecules (20 distinct):
DNA replication licensing factor MCM2
Molecule details ›
Chain: 2
Length: 868 amino acids
Theoretical weight: 98.91 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Trichoplusia ni
UniProt:
Sequence domains:
Length: 868 amino acids
Theoretical weight: 98.91 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Trichoplusia ni
UniProt:
- Canonical:
P29469 (Residues: 1-868; Coverage: 100%)
Sequence domains:
DNA replication licensing factor MCM3
Molecule details ›
Chain: 3
Length: 1009 amino acids
Theoretical weight: 111.99 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
Sequence domains:
Length: 1009 amino acids
Theoretical weight: 111.99 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
- Canonical: P24279 (Residues: 1-971; Coverage: 100%)
Sequence domains:
DNA replication licensing factor MCM4
Minichromosome maintenance protein 5
DNA replication licensing factor MCM6
DNA replication licensing factor MCM7
DNA primase large subunit
DNA polymerase alpha subunit B
DNA replication complex GINS protein PSF1
DNA replication complex GINS protein PSF2
DNA replication complex GINS protein PSF3
DNA replication complex GINS protein SLD5
Cell division control protein 45
Mediator of replication checkpoint protein 1
DNA primase small subunit
Topoisomerase 1-associated factor 1
Chromosome segregation in meiosis protein 3
DNA polymerase alpha catalytic subunit A
