EC 3.6.4.13: RNA helicase
Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Systematic name:
ATP phosphohydrolase (RNA helix unwinding)
Alternative Name(s):
- CSFV NS3 helicase
- DBP2
- DDX17
- DDX25
- DDX3
- DDX3X
- DDX3Y
- DDX4
- DDX5
- DEAD-box RNA helicase
- DEAD-box protein DED1
- DEAH-box RNA helicase
- DEAH-box protein 2
- DED1
- DbpA
- Dex(H/D) RNA helicase
- EIF4A helicase
- EhDEAD1
- EhDEAD1 RNA helicase
- GRTH/DDX25
- KOKV helicase
- Mtr4p
- NPH-II
- Nonstructural protein 3 helicase
- RHA
- RNA helicase A
- RNA helicase DDX3
- RNA helicase Hera
- RNA-dependent ATPase
- TGBp1 NTPase/helicase domain
- VRH1
GO terms
Biochemical function:
- lncRNA binding
- 3'-5' DNA helicase activity
- 3'-5' RNA helicase activity
- 3'-5' DNA/RNA helicase activity
- ATP hydrolysis activity
- hydrolase activity
- ATP binding
- helicase activity
- double-stranded RNA binding
- RNA helicase activity
- RNA binding
- double-stranded DNA binding
- chromatin binding
- DNA helicase activity
- nucleic acid binding
- regulatory region RNA binding
Biological process:
- regulation of cytoplasmic translation
- positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity
- regulation of mRNA processing
- axon extension
- positive regulation of transcription by RNA polymerase II
- male courtship behavior, veined wing generated song production
- dosage compensation complex assembly
- DNA duplex unwinding
- positive regulation of heterochromatin formation
- regulation of gene expression
- dosage compensation by hyperactivation of X chromosome
- determination of adult lifespan
- sex-chromosome dosage compensation