Protein Data Bank in Europe

Chains: A, S
Length: 4128 amino acids
Theoretical weight: 469.67 KDa
Source organism: Homo sapiens
UniProt:

• Canonical: P78527 (Residues: 1-4128; Coverage: 100%)

Gene names: HYRC, HYRC1, PRKDC
Sequence domains:

• DNA-dependent protein kinase catalytic subunit, CC1/2
• DNA-dependent protein kinase catalytic subunit, CC3
• DNA-PKcs, CC5
• FAT domain
• Phosphatidylinositol 3- and 4-kinase
• FATC domain

Chains: B, T
Length: 609 amino acids
Theoretical weight: 69.95 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:

• Canonical: P12956 (Residues: 1-609; Coverage: 100%)

Gene names: G22P1, XRCC6
Sequence domains:

• Ku70/Ku80 N-terminal alpha/beta domain
• Ku70/Ku80 beta-barrel domain
• Ku70/Ku80 C-terminal arm
• SAP domain

Chains: C, L
Length: 732 amino acids
Theoretical weight: 82.81 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:

• Canonical: P13010 (Residues: 1-732; Coverage: 100%)

Gene names: G22P2, XRCC5
Sequence domains:

• Ku70/Ku80 N-terminal alpha/beta domain
• Ku70/Ku80 beta-barrel domain
• Ku70/Ku80 C-terminal arm
• Ku C terminal domain like

Chains: D, M
Length: 204 amino acids
Theoretical weight: 21.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:

• Canonical: Q9BUH6 (Residues: 1-204; Coverage: 100%)

Gene names: C9orf142, PAXX, XLS
Sequence domains: PAXX, PAralog of XRCC4 and XLF, also called C9orf142

Chains: G, H, P, Q
Length: 336 amino acids
Theoretical weight: 38.34 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:

• Canonical: Q13426 (Residues: 1-336; Coverage: 100%)

Gene name: XRCC4
Sequence domains:

• XRCC4 N-terminal domain
• XRCC4 coiled-coil
• XRCC4 C-terminal region

Chains: I, R
Length: 911 amino acids
Theoretical weight: 104.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:

• Canonical: P49917 (Residues: 1-911; Coverage: 100%)

Gene name: LIG4
Sequence domains:

• DNA ligase N terminus
• ATP dependent DNA ligase domain
• ATP dependent DNA ligase C terminal region
• BRCA1 C Terminus (BRCT) domain
• DNA ligase IV

Chain: j
Length: 25 nucleotides
Theoretical weight: 7.75 KDa

Chain: i
Length: 27 nucleotides
Theoretical weight: 8.29 KDa

Chain: d
Length: 26 nucleotides
Theoretical weight: 8.04 KDa

Chain: e
Length: 28 nucleotides
Theoretical weight: 8.6 KDa