Function and Biology Details
Reactions catalysed:
ATP + a protein = ADP + a phosphoprotein
ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131170 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
DNA damage-binding protein 1
Molecule details ›
Chains: A, D, G
Length: 840 amino acids
Theoretical weight: 93.68 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains:
Length: 840 amino acids
Theoretical weight: 93.68 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical:
Q16531 (Residues: 1-395, 706-1140; Coverage: 73%) - Best match: Q16531-2 (Residues: 59-451)
Sequence domains:
Cyclin-dependent kinase 12
Molecule details ›
Chains: B, E, H
Length: 344 amino acids
Theoretical weight: 40.14 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains: Protein kinase domain
Length: 344 amino acids
Theoretical weight: 40.14 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical: Q9NYV4 (Residues: 712-1051; Coverage: 23%)
Sequence domains: Protein kinase domain
Cyclin-K
Molecule details ›
Chains: C, F, I
Length: 271 amino acids
Theoretical weight: 31.7 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains:
Length: 271 amino acids
Theoretical weight: 31.7 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical: O75909 (Residues: 1-267; Coverage: 46%)
Sequence domains:
