Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine
ATP + H(2)O = ADP + phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero 28-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-269054 (preferred)
Entry contents:
22 distinct polypeptide molecules
2 distinct DNA molecules
2 distinct DNA molecules
Macromolecules (24 distinct):
DNA-directed RNA polymerase subunit
Chain: A
DNA-directed RNA polymerase subunit beta
Chain: B
DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein
Chain: C
RNA polymerase Rpb4/RPC9 core domain-containing protein
Chain: D
DNA-directed RNA polymerase II subunit E
Chain: E
DNA-directed RNA polymerases I, II, and III subunit RPABC2
Chain: F
DNA-directed RNA polymerase II subunit RPB7
Chain: G
DNA-directed RNA polymerases I, II, and III subunit RPABC3
Chain: H
DNA-directed RNA polymerase II subunit RPB9
Chain: I
DNA-directed RNA polymerases I, II, and III subunit RPABC5
Chain: J
DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein
Chain: K
RNA polymerase II, I and III subunit K
Chain: L
Transcription initiation factor IIB
Chain: M
Molecule details ›
Chain: M
Length: 316 amino acids
Theoretical weight: 34.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Length: 316 amino acids
Theoretical weight: 34.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
TATA-box-binding protein
Chain: O
Molecule details ›
Chain: O
Length: 339 amino acids
Theoretical weight: 37.73 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Length: 339 amino acids
Theoretical weight: 37.73 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
General transcription factor IIF subunit 1
Chain: Q
Molecule details ›
Chain: Q
Length: 517 amino acids
Theoretical weight: 58.34 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Length: 517 amino acids
Theoretical weight: 58.34 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
General transcription factor IIF subunit 2
Chain: R
Molecule details ›
Chain: R
Length: 249 amino acids
Theoretical weight: 28.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Length: 249 amino acids
Theoretical weight: 28.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Transcription initiation factor IIA subunit 1
Chain: U
Molecule details ›
Chain: U
Length: 376 amino acids
Theoretical weight: 41.54 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Length: 376 amino acids
Theoretical weight: 41.54 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Transcription initiation factor IIA subunit 2
Chain: V
Molecule details ›
Chain: V
Length: 109 amino acids
Theoretical weight: 12.47 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Length: 109 amino acids
Theoretical weight: 12.47 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Histone H3.2
Chains: a, e
Molecule details ›
Chains: a, e
Length: 136 amino acids
Theoretical weight: 15.44 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
Length: 136 amino acids
Theoretical weight: 15.44 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
Histone H4
Chains: b, f
Molecule details ›
Chains: b, f
Length: 103 amino acids
Theoretical weight: 11.39 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
Length: 103 amino acids
Theoretical weight: 11.39 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
Histone H2A type 1
Chains: c, g
Molecule details ›
Chains: c, g
Length: 130 amino acids
Theoretical weight: 14.09 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
Length: 130 amino acids
Theoretical weight: 14.09 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
Histone H2B 1.1
Chains: d, h
Molecule details ›
Chains: d, h
Length: 126 amino acids
Theoretical weight: 13.97 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
Length: 126 amino acids
Theoretical weight: 13.97 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
Non-template DNA
Chain: N
Molecule details ›
Chain: N
Length: 210 nucleotides
Theoretical weight: 64.78 KDa
Source organism: unidentified adenovirus
Expression system: Not provided
Length: 210 nucleotides
Theoretical weight: 64.78 KDa
Source organism: unidentified adenovirus
Expression system: Not provided
Template DNA
Chain: T
Molecule details ›
Chain: T
Length: 210 nucleotides
Theoretical weight: 64.91 KDa
Source organism: unidentified adenovirus
Expression system: Not provided
Length: 210 nucleotides
Theoretical weight: 64.91 KDa
Source organism: unidentified adenovirus
Expression system: Not provided