Function and Biology Details
Reaction catalysed:
NADH + ubiquinone + 5 H(+)(Side 1) = NAD(+) + ubiquinol + 4 H(+)(Side 2)
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-237642 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial
Molecule details ›
Chain: E
Length: 248 amino acids
Theoretical weight: 27.32 KDa
Source organism: Mus musculus
UniProt:
Sequence domains: Thioredoxin-like [2Fe-2S] ferredoxin
Length: 248 amino acids
Theoretical weight: 27.32 KDa
Source organism: Mus musculus
UniProt:
- Canonical:
Q9D6J6 (Residues: 1-248; Coverage: 100%)
Sequence domains: Thioredoxin-like [2Fe-2S] ferredoxin
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
Molecule details ›
Chain: F
Length: 464 amino acids
Theoretical weight: 50.9 KDa
Source organism: Mus musculus
UniProt:
Sequence domains:
Length: 464 amino acids
Theoretical weight: 50.9 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q91YT0 (Residues: 1-464; Coverage: 100%)
Sequence domains:
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
Molecule details ›
Chain: G
Length: 727 amino acids
Theoretical weight: 79.87 KDa
Source organism: Mus musculus
UniProt:
Sequence domains:
Length: 727 amino acids
Theoretical weight: 79.87 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q91VD9 (Residues: 1-727; Coverage: 100%)
Sequence domains:
- 2Fe-2S iron-sulfur cluster binding domain
- NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
- NADH-quinone oxidoreductase subunit 3, ferredoxin-like domain
- NADH-ubiquinone oxidoreductase NDSU1/NuoG-like, 4Fe-4S domain
- Molybdopterin oxidoreductase
- NADH-ubiquinone oxidoreductase subunit G, C-terminal
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2
Molecule details ›
Chain: S
Length: 99 amino acids
Theoretical weight: 10.93 KDa
Source organism: Mus musculus
UniProt:
Sequence domains: Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
Length: 99 amino acids
Theoretical weight: 10.93 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q9CQ75 (Residues: 1-99; Coverage: 100%)
Sequence domains: Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
Molecule details ›
Chain: s
Length: 104 amino acids
Theoretical weight: 11.83 KDa
Source organism: Mus musculus
UniProt:
Sequence domains: NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
Length: 104 amino acids
Theoretical weight: 11.83 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q8BK30 (Residues: 1-104; Coverage: 100%)
Sequence domains: NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
