Function and Biology Details
Reaction catalysed:
S-adenosyl-L-methionine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(ribonucleotide)-[mRNA] = S-adenosyl-L-homocysteine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleotide)-[mRNA]
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-228419 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase
Molecule details ›
Chains: A, B
Length: 307 amino acids
Theoretical weight: 35.95 KDa
Source organism: Monkeypox virus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Poly A polymerase regulatory subunit
Length: 307 amino acids
Theoretical weight: 35.95 KDa
Source organism: Monkeypox virus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
A0A7H0DN74 (Residues: 1-307; Coverage: 92%)
Sequence domains: Poly A polymerase regulatory subunit
