› 8ckw

Electron Microscopy
3.12Å resolution

HIV-1 mature capsid pentamer from CA-IP6 CLPs

Released:
DOI: 10.2210/pdb8ckw/pdb
PDB entry 8ckw coloured by chain, front view.
PDB entry 8ckw coloured by chain, side view.
PDB entry 8ckw coloured by chain, top view.
Source organism: Human immunodeficiency virus 1
Primary publication:
Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding.
Stacey JCV, Tan A, Lu JM, James LC, Dick RA, Briggs JAG
OpenAccess logo Proc Natl Acad Sci U S A 120 e2220557120 (2023)
PMID: 37040417
Related structures: EMD-16704

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo pentadecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-232448 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Capsid protein p24 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 232 amino acids
Theoretical weight: 25.76 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P12493 (Residues: 132-363; Coverage: 46%)
Gene name: gag
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.12Å
Relevant EMDB volumes: EMD-16704
Expression system: Escherichia coli BL21

Quick links

Citations

2 review citations

HIV Infection: Shaping the Complex, Dynamic, and Interconnected Network of the Cytoskeleton.
Cabrera-Rodríguez et al. (2023)
1 more