› 8cpx

Electron Microscopy
1.76Å resolution

Human apoferritin after 488 nm laser exposure in presence of rsEGFP2

Released:
DOI: 10.2210/pdb8cpx/pdb
PDB entry 8cpx coloured by chain, front view.
PDB entry 8cpx coloured by chain, side view.
PDB entry 8cpx coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Super-resolution fluorescence imaging of cryosamples does not limit achievable resolution in cryoEM.
G F Last M, Noteborn WEM, Voortman LM, Sharp TH
J Struct Biol 108040 (2023)
PMID: 37918761
Related structures: EMD-16789

Function and Biology Details

Reaction catalysed: 
4 Fe(2+) + 4 H(+) + O(2) = 4 Fe(3+) + 2 H(2)O
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo 24-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136244 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ferritin heavy chain Chains: 1, 2, 4, 6, A, B, E, F, G, H, I, K, M, O, P, Q, S, U, W, X, Y, a, e, r
Molecule details ›
Chains: 1, 2, 4, 6, A, B, E, F, G, H, I, K, M, O, P, Q, S, U, W, X, Y, a, e, r
Length: 173 amino acids
Theoretical weight: 20.22 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02794 (Residues: 5-177; Coverage: 95%)
Gene names: FTH, FTH1, FTHL6, OK/SW-cl.84, PIG15
Sequence domains: Ferritin-like domain

Ligands and Environments

2 bound ligands:
Ligand NA 24 x NA
Ligand MG 14 x MG
1 modified residue:
Ligand CSX 24 x CSX

Experiments and Validation Details

Entry percentile scores
Resolution: 1.76Å
Relevant EMDB volumes: EMD-16789
Expression system: Escherichia coli

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