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Electron Microscopy
2.7Å resolution

Local refinement of Anykyrin-1 (N-terminal half of membrane binding domain) in Class 2 of erythrocyte ankyrin-1 complex

Released:
DOI: 10.2210/pdb8csv/pdb
PDB entry 8csv coloured by chain, front view.
PDB entry 8csv coloured by chain, side view.
PDB entry 8csv coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Architecture of the human erythrocyte ankyrin-1 complex.
Vallese F, Kim K, Yen LY, Johnston JD, Noble AJ, Calì T, Clarke OB
Nat Struct Mol Biol 29 706-718 (2022)
PMID: 35835865
Related structures: EMD-26972

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136110 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ankyrin-1 Chain: A
Molecule details ›
Chain: A
Length: 1881 amino acids
Theoretical weight: 206.52 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P16157 (Residues: 1-1881; Coverage: 100%)
Gene names: ANK, ANK1
Sequence domains:
Band 3 anion transport protein Chain: W
Molecule details ›
Chain: W
Length: 911 amino acids
Theoretical weight: 101.88 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02730 (Residues: 1-911; Coverage: 100%)
Gene names: AE1, DI, EPB3, SLC4A1
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.7Å
Relevant EMDB volumes: EMD-26972

Quick links

Citations

1 review citation

Alloimmune hemolytic disease of the fetus and newborn: genetics, structure, and function of the commonly involved erythrocyte antigens.
Christensen et al. (2023)
18 other articles

1 mention without citation

Architecture of the human erythrocyte ankyrin-1 complex.
Vallese et al. (2022)