8cvo

Electron Microscopy
2.95Å resolution

Cutibacterium acnes 30S ribosomal subunit with Sarecycline bound, head domain only in the local refined map

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
PDBe Complex ID:
PDB-CPX-250356 (preferred)
Entry contents:
8 distinct polypeptide molecules
1 distinct RNA molecule
Macromolecules (9 distinct):
Small ribosomal subunit protein uS5 Chain: E
Molecule details ›
Chain: E
Length: 215 amino acids
Theoretical weight: 22.6 KDa
Source organism: Cutibacterium acnes
UniProt:
  • Canonical: Q6A6P3 (Residues: 1-215; Coverage: 100%)
Gene names: PPA1844, rpsE
Sequence domains:
Small ribosomal subunit protein uS3 Chain: G
Molecule details ›
Chain: G
Length: 269 amino acids
Theoretical weight: 29.73 KDa
Source organism: Cutibacterium acnes
UniProt:
  • Canonical: Q6A6N2 (Residues: 1-269; Coverage: 100%)
Gene names: PPA1857, rpsC
Sequence domains:
Small ribosomal subunit protein uS7 Chain: I
Molecule details ›
Chain: I
Length: 156 amino acids
Theoretical weight: 17.62 KDa
Source organism: Cutibacterium acnes
UniProt:
  • Canonical: Q6A6L4 (Residues: 1-156; Coverage: 100%)
Gene names: PPA1876, rpsG
Sequence domains: Ribosomal protein S7p/S5e
Small ribosomal subunit protein uS9 Chain: J
Molecule details ›
Chain: J
Length: 173 amino acids
Theoretical weight: 18.63 KDa
Source organism: Cutibacterium acnes
UniProt:
  • Canonical: Q6A6T4 (Residues: 1-173; Coverage: 100%)
Gene names: PPA1802, rpsI
Sequence domains: Ribosomal protein S9/S16
Small ribosomal subunit protein uS10 Chain: M
Molecule details ›
Chain: M
Length: 103 amino acids
Theoretical weight: 11.75 KDa
Source organism: Cutibacterium acnes
UniProt:
  • Canonical: Q6A6M5 (Residues: 1-103; Coverage: 100%)
Gene names: PPA1865, rpsJ
Sequence domains: Ribosomal protein S10p/S20e
Small ribosomal subunit protein uS13 Chain: N
Molecule details ›
Chain: N
Length: 123 amino acids
Theoretical weight: 14.03 KDa
Source organism: Cutibacterium acnes
UniProt:
  • Canonical: Q6A6Q8 (Residues: 1-123; Coverage: 100%)
Gene names: PPA1829, rpsM
Sequence domains: Ribosomal protein S13/S18
Small ribosomal subunit protein uS14B Chain: S
Molecule details ›
Chain: S
Length: 61 amino acids
Theoretical weight: 6.92 KDa
Source organism: Cutibacterium acnes
UniProt:
  • Canonical: Q6A6N9 (Residues: 1-61; Coverage: 100%)
Gene names: PPA1849, rpsN1, rpsZ
Sequence domains: Ribosomal protein S14p/S29e
Small ribosomal subunit protein uS19 Chain: U
Molecule details ›
Chain: U
Length: 93 amino acids
Theoretical weight: 10.54 KDa
Source organism: Cutibacterium acnes
UniProt:
  • Canonical: Q6A6N0 (Residues: 1-93; Coverage: 100%)
Gene names: PPA1859, rpsS
Sequence domains: Ribosomal protein S19
16S ribosomal RNA Chain: A
Molecule details ›
Chain: A
Length: 1537 nucleotides
Theoretical weight: 498.74 KDa
Sequence domains: Bacterial small subunit ribosomal RNA

Ligands and Environments

Experiments and Validation Details

Entry percentile scores
Resolution: 2.95Å
Relevant EMDB volumes: EMD-27011