Function and Biology Details
Reaction catalysed:
Cytosine in single-stranded DNA + H(2)O = uracil in single-stranded DNA + NH(3)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Retroviral Vif (Viral infectivity) protein
- Ubiquitin-like domain
- SKP1/BTB/POZ domain superfamily
- Core-binding factor, beta subunit superfamily
- Core-binding factor, beta subunit
- Cytidine and deoxycytidylate deaminase domain
- SKP1 component, POZ domain
- S-phase kinase-associated protein 1-like
5 more domains
Structure analysis Details
Assembly composition:
hetero dodecamer (preferred)
PDBe Complex ID:
PDB-CPX-246640 (preferred)
Entry contents:
5 distinct polypeptide molecules
2 distinct RNA molecules
2 distinct RNA molecules
Macromolecules (7 distinct):
DNA dC->dU-editing enzyme APOBEC-3G
Molecule details ›
Chains: A, F
Length: 421 amino acids
Theoretical weight: 50.03 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Length: 421 amino acids
Theoretical weight: 50.03 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
Q9HC16 (Residues: 1-384; Coverage: 100%)
Sequence domains:
Virion infectivity factor
Molecule details ›
Chains: B, G
Length: 192 amino acids
Theoretical weight: 22.56 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Retroviral Vif (Viral infectivity) protein
Length: 192 amino acids
Theoretical weight: 22.56 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: P69723 (Residues: 1-192; Coverage: 100%)
Sequence domains: Retroviral Vif (Viral infectivity) protein
Core-binding factor subunit beta
Elongin-B
Elongin-C
