8czo

Electron Microscopy
4.3Å resolution

Cryo-EM structure of BCL10 CARD - MALT1 DD filament

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero 44-mer (preferred)
PDBe Complex ID:
PDB-CPX-523161 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 Chains: a, b, c, d, e, f, g, h, i, j, k, l, m, n, o, p, q, r, s, t, u, v
Molecule details ›
Chains: a, b, c, d, e, f, g, h, i, j, k, l, m, n, o, p, q, r, s, t, u, v
Length: 94 amino acids
Theoretical weight: 10.62 KDa
Source organism: Homo sapiens
Expression system: Escherichia phage EcSzw-2
UniProt:
  • Canonical: Q9UDY8 (Residues: 29-122; Coverage: 11%)
Gene names: MALT1, MLT
B-cell lymphoma/leukemia 10 Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V
Length: 106 amino acids
Theoretical weight: 12.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia phage EcSzw-2
UniProt:
  • Canonical: O95999 (Residues: 10-115; Coverage: 46%)
Gene names: BCL10, CIPER, CLAP
Sequence domains: Caspase recruitment domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.3Å
Relevant EMDB volumes: EMD-27100
Expression system: Escherichia phage EcSzw-2