8d01

X-ray diffraction
2.46Å resolution

The domain-swaped dimer of the HIV-1 CD4bs targeting antibody 21N13

Released:
Source organism: Macaca mulatta
Entry authors: Xian Y, Wilson IA

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-236566 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
21N13 Fab heavy chain Chains: A, H
Molecule details ›
Chains: A, H
Length: 225 amino acids
Theoretical weight: 24.37 KDa
Source organism: Macaca mulatta
Expression system: Homo sapiens
21N13 Fab light chain Chains: B, L
Molecule details ›
Chains: B, L
Length: 213 amino acids
Theoretical weight: 23.41 KDa
Source organism: Macaca mulatta
Expression system: Homo sapiens

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: C2
Unit cell:
a: 260.367Å b: 45.151Å c: 84.61Å
α: 90° β: 98.609° γ: 90°
R-values:
R R work R free
0.191 0.189 0.229
Expression system: Homo sapiens