› 8d14

Electron Microscopy
2.51Å resolution

Helical ADP-Pi-F-actin

Released:
DOI: 10.2210/pdb8d14/pdb
PDB entry 8d14 coloured by chain, front view.
PDB entry 8d14 coloured by chain, side view.
PDB entry 8d14 coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
Bending forces and nucleotide state jointly regulate F-actin structure.
Reynolds MJ, Hachicho C, Carl AG, Gong R, Alushin GM
OpenAccess logo Nature (2022)
PMID: 36289330
Related structures: EMD-27115

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159345 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Actin, alpha skeletal muscle Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 377 amino acids
Theoretical weight: 42.11 KDa
Source organism: Gallus gallus
UniProt:
  • Canonical: P68139 (Residues: 1-377; Coverage: 100%)
Gene names: ACTA, ACTA1
Sequence domains: Actin

Ligands and Environments

3 bound ligands:
Ligand ADP 3 x ADP
Ligand MG 3 x MG
Ligand PO4 3 x PO4
1 modified residue:
Ligand HIC 3 x HIC

Experiments and Validation Details

Entry percentile scores
Resolution: 2.51Å
Relevant EMDB volumes: EMD-27115

Quick links

Citations

3 review citations

Bending actin filaments: twists of fate.
Nakamura et al. (2023)
2 more