› 8d6u

X-ray diffraction
2.65Å resolution

Rana catesbeiana saxiphilin:F-STX (soaked)

Released:
DOI: 10.2210/pdb8d6u/pdb
PDB entry 8d6u coloured by chain, front view.
PDB entry 8d6u coloured by chain, side view.
PDB entry 8d6u coloured by chain, top view.
Source organism: Lithobates catesbeianus
Primary publication:
Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family.
Chen Z, Zakrzewska S, Hajare HS, Alvarez-Buylla A, Abderemane-Ali F, Bogan M, Ramirez D, O'Connell LA, Du Bois J, Minor DL
OpenAccess logo Proc Natl Acad Sci U S A 119 e2210114119 (2022)
PMID: 36279441

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151972 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Saxiphilin Chains: A, B
Molecule details ›
Chains: A, B
Length: 853 amino acids
Theoretical weight: 94.23 KDa
Source organism: Lithobates catesbeianus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P31226 (Residues: 1-844; Coverage: 100%)
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand QDX 2 x QDX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: P212121
Unit cell:
a: 96.437Å b: 109.37Å c: 256.361Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.237 0.236 0.266
Expression system: Spodoptera frugiperda

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Citations

2 citation in other articles

Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family.
Chen et al. (2022)
1 more