Function and Biology Details
Reaction catalysed:
Endonucleolytic cleavage to 5'-phosphomonoester.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Protein Loquacious and Endoribonuclease Dcr-1 (preferred)
PDBe Complex ID:
PDB-CPX-577898 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Endoribonuclease Dcr-1
Molecule details ›
Chain: A
Length: 2249 amino acids
Theoretical weight: 255.73 KDa
Source organism: Drosophila melanogaster
Expression system: unidentified baculovirus
UniProt:
Sequence domains:
Length: 2249 amino acids
Theoretical weight: 255.73 KDa
Source organism: Drosophila melanogaster
Expression system: unidentified baculovirus
UniProt:
- Canonical:
Q9VCU9 (Residues: 1-2249; Coverage: 100%)
Sequence domains:
Protein Loquacious
Molecule details ›
Chain: N
Length: 465 amino acids
Theoretical weight: 50.15 KDa
Source organism: Drosophila melanogaster
Expression system: unidentified baculovirus
UniProt:
Sequence domains: Double-stranded RNA binding motif
Length: 465 amino acids
Theoretical weight: 50.15 KDa
Source organism: Drosophila melanogaster
Expression system: unidentified baculovirus
UniProt:
- Canonical: Q9VJY9 (Residues: 1-465; Coverage: 100%)
Sequence domains: Double-stranded RNA binding motif
