Function and Biology Details
Reactions catalysed:
ATP + a protein = ADP + a phosphoprotein
ATP + L-seryl/L-threonyl/L-tyrosyl-[protein] = ADP + O-phospho-L-seryl/O-phospho-L-threonyl/O-phospho-L-tyrosyl-[protein]
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-235724 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Serine/threonine-protein kinase B-raf
Molecule details ›
Chain: A
Length: 805 amino acids
Theoretical weight: 89.4 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Length: 805 amino acids
Theoretical weight: 89.4 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P15056 (Residues: 1-766; Coverage: 100%)
Sequence domains:
Dual specificity mitogen-activated protein kinase kinase 1
Molecule details ›
Chain: B
Length: 414 amino acids
Theoretical weight: 45.84 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Protein kinase domain
Length: 414 amino acids
Theoretical weight: 45.84 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: Q02750 (Residues: 1-392; Coverage: 100%)
Sequence domains: Protein kinase domain
14-3-3 domain-containing protein
GTPase KRas, N-terminally processed
