Function and Biology Details
Reaction catalysed:
RX + glutathione = HX + R-S-glutathione
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Folliculin-interacting protein family
- Ragulator complex protein LAMTOR5
- Glutathione S-transferase, N-terminal
- Gtr1/RagA G protein
- P-loop containing nucleoside triphosphate hydrolase
- Glutathione S-transferase, C-terminal
- Glutathione S-transferase, C-terminal-like
- Glutathione S-transferase, C-terminal domain superfamily
18 more domains
Structure analysis Details
Assembly composition:
hetero decamer (preferred)
Assembly name:
Ragulator complex (preferred)
PDBe Complex ID:
PDB-CPX-275950 (preferred)
Entry contents:
10 distinct polypeptide molecules
Macromolecules (10 distinct):
Ras-related GTP-binding protein C
Molecule details ›
Chain: A
Length: 400 amino acids
Theoretical weight: 44.38 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Gtr1/RagA G protein conserved region
Length: 400 amino acids
Theoretical weight: 44.38 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
Q9HB90 (Residues: 1-399; Coverage: 100%)
Sequence domains: Gtr1/RagA G protein conserved region
Ras-related GTP-binding protein A
Molecule details ›
Chain: B
Length: 336 amino acids
Theoretical weight: 39.36 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Gtr1/RagA G protein conserved region
Length: 336 amino acids
Theoretical weight: 39.36 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: Q7L523 (Residues: 1-313; Coverage: 100%)
Sequence domains: Gtr1/RagA G protein conserved region
Ragulator complex protein LAMTOR1
Ragulator complex protein LAMTOR2
Ragulator complex protein LAMTOR3
Ragulator complex protein LAMTOR4
Ragulator complex protein LAMTOR5
Glutathione S-transferase class-mu 26 kDa isozyme; Neutral amino acid transporter 9
Folliculin-interacting protein 2
Folliculin
