› 8dim

Electron Microscopy
2.62Å resolution

CryoEM structure of Influenza A virus A/Ohio/09/2015 hemagglutinin bound to CR6261 Fab

Released:
DOI: 10.2210/pdb8dim/pdb
PDB entry 8dim coloured by chain, front view.
PDB entry 8dim coloured by chain, side view.
PDB entry 8dim coloured by chain, top view.
Source organisms:
Entry author: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Related structures: EMD-27440

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-224672 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Hemagglutinin HA2 chain Chains: A, D, G
Molecule details ›
Chains: A, D, G
Length: 576 amino acids
Theoretical weight: 64.43 KDa
Source organism: Influenza A virus
Expression system: Trichoplusia ni
UniProt:
  • Canonical: A0A6C0TB04 (Residues: 2-17, 18-509; Coverage: 90%)
Gene name: HA
Sequence domains: Haemagglutinin
CR6261 Fab heavy chain Chains: B, E, H
Molecule details ›
Chains: B, E, H
Length: 251 amino acids
Theoretical weight: 27.07 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
CR6261 Fab light chain Chains: C, F, I
Molecule details ›
Chains: C, F, I
Length: 240 amino acids
Theoretical weight: 25.51 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
1 bound ligand:
Ligand NAG 9 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.62Å
Relevant EMDB volumes: EMD-27440
Expression systems:
  • Trichoplusia ni
  • Homo sapiens

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