8dki

Electron Microscopy
3.32Å resolution

Cryo-EM structure of cystinosin in a lumen-open state

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-271800 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Cystinosin Chain: P
Molecule details ›
Chain: P
Length: 408 amino acids
Theoretical weight: 46.08 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Fab 3H5 Heavy Chain Chain: A
Molecule details ›
Chain: A
Length: 250 amino acids
Theoretical weight: 26.77 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
Fab 3H5 Kappa chain Chain: B

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.32Å
Relevant EMDB volumes: EMD-27489
Expression system: Homo sapiens