8dny

Electron Microscopy
2.85Å resolution

Cryo-EM structure of the human Sec61 complex inhibited by decatransin

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-274020 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Protein transport protein Sec61 subunit alpha isoform 1 Chain: A
Molecule details ›
Chain: A
Length: 476 amino acids
Theoretical weight: 52.2 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
Protein transport protein Sec61 subunit gamma Chain: B
Molecule details ›
Chain: B
Length: 68 amino acids
Theoretical weight: 7.75 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
Protein transport protein Sec61 subunit beta Chain: C
Decatransin peptide inhibitor Chain: D

Ligands and Environments

No bound ligands
3 modified residues:

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 2.85Å
Relevant EMDB volumes: EMD-27584
Expression systems:
  • Spodoptera frugiperda
  • Not provided