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Structure of LRRC8C-LRRC8A(IL125) Chimera, Class 2

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

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GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF13855
Domain description: Leucine rich repeat
Occurring in:
  1. Volume-regulated anion channel subunit LRRC8A; Volume-regulated anion channel subunit LRRC8C
The deposited structure of PDB entry 8dxo contains 14 copies of Pfam domain PF13855 (Leucine rich repeat) in Volume-regulated anion channel subunit LRRC8A. Showing 2 copies in chain F (this domain is out of the observed residue ranges!).

PF12534
Domain description: Pannexin-like TM region of LRRC8
Occurring in:
  1. Volume-regulated anion channel subunit LRRC8A; Volume-regulated anion channel subunit LRRC8C
The deposited structure of PDB entry 8dxo contains 14 copies of Pfam domain PF12534 (Pannexin-like TM region of LRRC8) in Volume-regulated anion channel subunit LRRC8A. Showing 2 copies in chain F.

InterPro InterPro annotations
IPR003591
Domain description: Leucine-rich repeat, typical subtype
Occurring in:
  1. Volume-regulated anion channel subunit LRRC8A; Volume-regulated anion channel subunit LRRC8C
IPR001611
Domain description: Leucine-rich repeat
Occurring in:
  1. Volume-regulated anion channel subunit LRRC8A; Volume-regulated anion channel subunit LRRC8C
IPR026906
Domain description: BspA-type LRR region
Occurring in:
  1. Volume-regulated anion channel subunit LRRC8A; Volume-regulated anion channel subunit LRRC8C
IPR032675
Domain description: Leucine-rich repeat domain superfamily
Occurring in:
  1. Volume-regulated anion channel subunit LRRC8A; Volume-regulated anion channel subunit LRRC8C
IPR021040
Domain description: LRRC8, pannexin-like TM region
Occurring in:
  1. Volume-regulated anion channel subunit LRRC8A; Volume-regulated anion channel subunit LRRC8C

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