8dxt

X-ray diffraction
2.25Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-535105 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Light chain of Fab arm of antibody GAR12 Chain: L
Molecule details ›
Chain: L
Length: 214 amino acids
Theoretical weight: 23.35 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
Heavy chain of Fab arm of antibody GAR12 Chain: H
Molecule details ›
Chain: H
Length: 234 amino acids
Theoretical weight: 24.77 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
Spike protein S1 Chain: R
Molecule details ›
Chain: R
Length: 204 amino acids
Theoretical weight: 22.98 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P0DTC2 (Residues: 333-528; Coverage: 16%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, FUC
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Unit cell:
a: 93.609Å b: 41.954Å c: 183.029Å
α: 90° β: 97.08° γ: 90°
R-values:
R R work R free
0.213 0.211 0.254
Expression system: Cricetulus griseus