› 8dxt

X-ray diffraction
2.25Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-272893 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Light chain of Fab arm of antibody GAR12 Chain: L
Molecule details ›
Chain: L
Length: 214 amino acids
Theoretical weight: 23.35 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
Heavy chain of Fab arm of antibody GAR12 Chain: H
Molecule details ›
Chain: H
Length: 234 amino acids
Theoretical weight: 24.77 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
Spike protein S1 Chain: R

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, FUC
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Unit cell:
a: 93.609Å b: 41.954Å c: 183.029Å
α: 90° β: 97.08° γ: 90°
R-values:
R R work R free
0.213 0.211 0.254
Expression system: Cricetulus griseus

Quick links

Citations

1 review citation

Comprehensive Overview of Broadly Neutralizing Antibodies against SARS-CoV-2 Variants.
Cui et al. (2024)
12 other articles

2 mentions without citation

Widespread impact of immunoglobulin V-gene allelic polymorphisms on antibody reactivity.
Yuan et al. (2023)
1 more