8dzi

Electron Microscopy
3.5Å resolution

Structure of SARS-CoV-2 Omicron BA.1.1.529 Spike trimer with one RBD down in complex with the Fab fragment of human neutralizing antibody MB.02

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
PDBe Complex ID:
PDB-CPX-276130 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Spike glycoprotein Chains: A, C, E
Molecule details ›
Chains: A, C, E
Length: 1285 amino acids
Theoretical weight: 142.59 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 1-210, 211-1208; Coverage: 94%)
Gene names: 2, S
Sequence domains:
antibody MB.02 heavy chain Chains: B, G, H
Molecule details ›
Chains: B, G, H
Length: 118 amino acids
Theoretical weight: 12.97 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
antibody MB.02 light chain Chains: D, F, L
Molecule details ›
Chains: D, F, L
Length: 109 amino acids
Theoretical weight: 11.68 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.5Å
Relevant EMDB volumes: EMD-27799
Expression system: Homo sapiens