Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
Selective cleavage of Tyr-|-Gly bond in picornavirus polyprotein.
NTP + H(2)O = NDP + phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero 180-mer (preferred)
Assembly name:
VP2 (preferred)
PDBe Complex ID:
PDB-CPX-227619 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
VP1
Molecule details ›
Chain: A
Length: 225 amino acids
Theoretical weight: 25.37 KDa
Source organism: Enterovirus A71
Expression system: Homo sapiens
UniProt:
Length: 225 amino acids
Theoretical weight: 25.37 KDa
Source organism: Enterovirus A71
Expression system: Homo sapiens
UniProt:
- Canonical:
G9I191 (Residues: 637-861; Coverage: 10%)
VP2
Molecule details ›
Chain: B
Length: 235 amino acids
Theoretical weight: 25.8 KDa
Source organism: Enterovirus A71
Expression system: Homo sapiens
UniProt:
Length: 235 amino acids
Theoretical weight: 25.8 KDa
Source organism: Enterovirus A71
Expression system: Homo sapiens
UniProt:
- Canonical: G9I191 (Residues: 85-319; Coverage: 11%)
VP3
Molecule details ›
Chain: C
Length: 236 amino acids
Theoretical weight: 25.81 KDa
Source organism: Enterovirus A71
Expression system: Homo sapiens
UniProt:
Length: 236 amino acids
Theoretical weight: 25.81 KDa
Source organism: Enterovirus A71
Expression system: Homo sapiens
UniProt:
- Canonical: G9I191 (Residues: 324-559; Coverage: 11%)
