Function and Biology Details
Reaction catalysed:
Cytosine in single-stranded DNA + H(2)O = uracil in single-stranded DNA + NH(3)
Structure analysis Details
Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-223602 (preferred)
Entry contents:
3 distinct polypeptide molecules
2 distinct RNA molecules
2 distinct RNA molecules
Macromolecules (5 distinct):
DNA dC->dU-editing enzyme APOBEC-3G
Molecule details ›
Chain: A
Length: 386 amino acids
Theoretical weight: 45.19 KDa
Source organism: Macaca mulatta
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 386 amino acids
Theoretical weight: 45.19 KDa
Source organism: Macaca mulatta
Expression system: Escherichia coli
UniProt:
- Canonical:
Q7YR23 (Residues: 1-370; Coverage: 99%)
Sequence domains:
Virion infectivity factor
Molecule details ›
Chain: B
Length: 178 amino acids
Theoretical weight: 21.14 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Escherichia coli
UniProt:
Sequence domains: Retroviral Vif (Viral infectivity) protein
Length: 178 amino acids
Theoretical weight: 21.14 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Escherichia coli
UniProt:
- Canonical: P12504 (Residues: 1-176; Coverage: 92%)
Sequence domains: Retroviral Vif (Viral infectivity) protein
Core-binding factor subunit beta
Molecule details ›
Chain: C
Length: 157 amino acids
Theoretical weight: 18.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Core binding factor beta subunit
Length: 157 amino acids
Theoretical weight: 18.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q13951 (Residues: 1-157; Coverage: 86%)
Sequence domains: Core binding factor beta subunit
