Structure analysis

CryoEM structure of miniGq-coupled hM3R in complex with iperoxo (local refinement)

Electron Microscopy
2.56Å resolution
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: monomeric
Accessible surface area: 14903.7 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-148928

Macromolecules

Chain: A
Length: 568 amino acids
Theoretical weight: 62.97 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P20309 (Residues: 46-590; Coverage: 62%)
Gene name: CHRM3
Pfam: 7 transmembrane receptor (rhodopsin family)
InterPro:
PDBe-KB: UniProt Coverage View: P20309  
156850100150200250300350400450500550
 
200400
UniProt
P20309
Chains
Domains
Secondary structure
Ligand binding sites
Sequence conservation

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