Function and Biology

CryoEM structure of miniGq-coupled hM3R in complex with iperoxo (local refinement)

Source organism: Homo sapiens
Biochemical function: G protein-coupled acetylcholine receptor activity
Biological process: saliva secretion
Cellular component: membrane

Sequence family

Pfam Protein family (Pfam)
PF00001
Domain description: 7 transmembrane receptor (rhodopsin family)
Occurring in:
  1. Muscarinic acetylcholine receptor M3
The deposited structure of PDB entry 8ea0 contains 1 copy of Pfam domain PF00001 (7 transmembrane receptor (rhodopsin family)) in Muscarinic acetylcholine receptor M3. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000276
Domain description: G protein-coupled receptor, rhodopsin-like
Occurring in:
  1. Muscarinic acetylcholine receptor M3
IPR000995
Domain description: Muscarinic acetylcholine receptor family
Occurring in:
  1. Muscarinic acetylcholine receptor M3
IPR012674
Domain description: Calycin
Occurring in:
  1. Muscarinic acetylcholine receptor M3
IPR001183
Domain description: Muscarinic acetylcholine receptor M3
Occurring in:
  1. Muscarinic acetylcholine receptor M3
IPR017452
Domain description: GPCR, rhodopsin-like, 7TM
Occurring in:
  1. Muscarinic acetylcholine receptor M3