Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dodecamer (preferred)
PDBe Complex ID:
PDB-CPX-172268 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Kelch domain-containing protein 2
Molecule details ›
Chains: A, B
Length: 406 amino acids
Theoretical weight: 46.15 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains: Galactose oxidase, central domain
Length: 406 amino acids
Theoretical weight: 46.15 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical:
Q9Y2U9 (Residues: 1-406; Coverage: 100%)
Sequence domains: Galactose oxidase, central domain
Elongin-B
Molecule details ›
Chains: C, E
Length: 104 amino acids
Theoretical weight: 11.75 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains: Ubiquitin family
Length: 104 amino acids
Theoretical weight: 11.75 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical: Q15370 (Residues: 1-104; Coverage: 88%)
Sequence domains: Ubiquitin family
Elongin-C
Molecule details ›
Chains: D, F
Length: 121 amino acids
Theoretical weight: 13.95 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains: Skp1 family, tetramerisation domain
Length: 121 amino acids
Theoretical weight: 13.95 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical: Q15369 (Residues: 16-112; Coverage: 87%)
Sequence domains: Skp1 family, tetramerisation domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 24-ID-C
Spacegroup:
P3112
Expression system: Trichoplusia ni
