› 8edn

Electron Microscopy
3.8Å resolution

Cryo-EM structure of the full-length human NF1 dimer

Released:
DOI: 10.2210/pdb8edn/pdb
PDB entry 8edn coloured by chain, front view.
PDB entry 8edn coloured by chain, side view.
PDB entry 8edn coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Darling JE, Merk A, Grisshammer R, Ognjenovic J
Related structures: EMD-28037

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149213 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neurofibromin Chain: A
Molecule details ›
Chain: A
Length: 2818 amino acids
Theoretical weight: 317.41 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P21359 (Residues: 1-2839; Coverage: 99%)
  • Best match: P21359-2 (Residues: 1-2818)
Gene name: NF1
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 3.8Å
Relevant EMDB volumes: EMD-28037
Expression system: Spodoptera frugiperda

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