› 8edo

Electron Microscopy
3.4Å resolution

Cryo-EM structure of the full-length human NF1 dimer

Released:
DOI: 10.2210/pdb8edo/pdb
PDB entry 8edo coloured by chain, front view.
PDB entry 8edo coloured by chain, side view.
PDB entry 8edo coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Darling JE, Merk A, Grisshammer R, Ognjenovic J
Related structures: EMD-28038

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149214 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neurofibromin truncated Chains: A, B
Molecule details ›
Chains: A, B
Length: 1264 amino acids
Theoretical weight: 142.49 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P21359 (Residues: 1039-2302; Coverage: 45%)
Gene name: NF1
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.4Å
Relevant EMDB volumes: EMD-28038
Expression system: Spodoptera frugiperda

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