› 8eea

Electron Microscopy
2.6Å resolution

Structure of E.coli Septu (PtuAB) complex

Released:
DOI: 10.2210/pdb8eea/pdb
PDB entry 8eea coloured by chain, front view.
PDB entry 8eea coloured by chain, side view.
PDB entry 8eea coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
PtuA and PtuB assemble into an inflammasome-like oligomer for anti-phage defense.
Li Y, Shen Z, Zhang M, Yang XY, Cleary SP, Xie J, Marathe IA, Kostelic M, Greenwald J, Rish AD, Wysocki VH, Chen C, Chen Q, Fu TM, Yu Y
Nat Struct Mol Biol (2024)
PMID: 38177683
Related structures: EMD-28049

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-237516 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
PtuA Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 465 amino acids
Theoretical weight: 53.19 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
TIGR02646 family protein Chains: G, H
Molecule details ›
Chains: G, H
Length: 243 amino acids
Theoretical weight: 28.14 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A6G1XJN6 (Residues: 1-243; Coverage: 100%)
Gene name: GIY10_13955

Ligands and Environments

1 bound ligand:
Ligand ATP 4 x ATP
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.6Å
Relevant EMDB volumes: EMD-28049
Expression system: Escherichia coli

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