› › Function and Biology

Rabbit muscle aldolase determined using single-particle cryo-EM with Apollo camera.

Source organism: Oryctolagus cuniculus
Biochemical function: lyase activity
Biological process: protein homotetramerization
Cellular component: I band

Quick links

EC 4.1.2.13: Fructose-bisphosphate aldolase

Reaction catalysed:
D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate
Systematic name:
D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase (glycerone-phosphate-forming)
Alternative Name(s):
  • 1,6-diphosphofructose aldolase
  • Aldolase
  • D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase
  • Diphosphofructose aldolase
  • Fructoaldolase
  • Fructose 1,6-diphosphate aldolase
  • Fructose 1-monophosphate aldolase
  • Fructose 1-phosphate aldolase
  • Fructose diphosphate aldolase
  • Fructose-1,6-bisphosphate triosephosphate-lyase
  • Ketose 1-phosphate aldolase
  • Phosphofructoaldolase
  • SMALDO
  • Zymohexase

GO terms

Sequence family

Pfam Protein family (Pfam)
PF00274
Domain description: Fructose-bisphosphate aldolase class-I
Occurring in:
  1. Fructose-bisphosphate aldolase A
The deposited structure of PDB entry 8ehg contains 4 copies of Pfam domain PF00274 (Fructose-bisphosphate aldolase class-I) in Fructose-bisphosphate aldolase A. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000741
Domain description: Fructose-bisphosphate aldolase, class-I
Occurring in:
  1. Fructose-bisphosphate aldolase A
IPR029768
Domain description: Fructose-bisphosphate aldolase class-I active site
Occurring in:
  1. Fructose-bisphosphate aldolase A
IPR013785
Domain description: Aldolase-type TIM barrel
Occurring in:
  1. Fructose-bisphosphate aldolase A

Quick links