8ejd

Electron Microscopy
3.8Å resolution

Structure of lineage IV Lassa virus glycoprotein complex (strain Josiah)

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140273 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (7 distinct):
Glycoprotein G1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 259 amino acids
Theoretical weight: 29.1 KDa
Source organism: Mammarenavirus lassaense
Expression system: Homo sapiens
UniProt:
  • Canonical: P08669 (Residues: 1-259; Coverage: 53%)
Gene names: GP-C, GPC
Sequence domains: Arenavirus glycoprotein
Glycoprotein G2 Chains: a, b, c
Molecule details ›
Chains: a, b, c
Length: 406 amino acids
Theoretical weight: 44.77 KDa
Source organism: Mammarenavirus lassaense
Expression system: Homo sapiens
UniProt:
  • Canonical: P08669 (Residues: 260-424; Coverage: 34%)
Gene names: GP-C, GPC
Sequence domains: Arenavirus glycoprotein

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, FUC
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.8Å
Relevant EMDB volumes: EMD-28178
Expression system: Homo sapiens