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Electron Microscopy
2.83Å resolution

Cryo-EM structure of human PRDX4

Released:
Source organism: Homo sapiens
Primary publication:
High-resolution structural-omics of human liver enzymes.
OpenAccess logo Cell Rep 42 112609 (2023)
PMID: 37289586
Related structures: EMD-23432, EMD-28214

Function and Biology Details

Reaction catalysed:
Thioredoxin + ROOH = thioredoxin disulfide + H(2)O + ROH
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo decamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171577 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peroxiredoxin-4 Chains: A, B, C, D, E, F, G, H, I, J
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J
Length: 271 amino acids
Theoretical weight: 30.58 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q13162 (Residues: 1-271; Coverage: 100%)
Gene name: PRDX4
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.83Å
Relevant EMDB volumes: EMD-23432, EMD-28214