› › Function and Biology

CryoEM structure of PN45545 TCR-CD3 complex

Source organism: Homo sapiens
Biochemical function: transmembrane signaling receptor activity
Biological process: cell surface receptor signaling pathway
Cellular component: membrane

Quick links

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF02189
Domain description: Immunoreceptor tyrosine-based activation motif
Occurring in:
  1. T-cell surface glycoprotein CD3 delta chain
  2. T-cell surface glycoprotein CD3 epsilon chain
  3. T-cell surface glycoprotein CD3 gamma chain
  4. T-cell surface glycoprotein CD3 zeta chain
The deposited structure of PDB entry 8es7 contains 4 copies of Pfam domain PF02189 (Immunoreceptor tyrosine-based activation motif) in T-cell surface glycoprotein CD3 zeta chain. Showing 2 copies in chain A [auth Z] (this domain is out of the observed residue ranges!).
The deposited structure of PDB entry 8es7 contains 1 copy of Pfam domain PF02189 (Immunoreceptor tyrosine-based activation motif) in T-cell surface glycoprotein CD3 delta chain. Showing 1 copy in chain C [auth D] (this domain is out of the observed residue ranges!).
The deposited structure of PDB entry 8es7 contains 2 copies of Pfam domain PF02189 (Immunoreceptor tyrosine-based activation motif) in T-cell surface glycoprotein CD3 epsilon chain. Showing 1 copy in chain D [auth F] (this domain is out of the observed residue ranges!).
The deposited structure of PDB entry 8es7 contains 1 copy of Pfam domain PF02189 (Immunoreceptor tyrosine-based activation motif) in T-cell surface glycoprotein CD3 gamma chain. Showing 1 copy in chain E [auth G] (this domain is out of the observed residue ranges!).

PF11628
Domain description: T-cell surface glycoprotein CD3 zeta chain
Occurring in:
  1. T-cell surface glycoprotein CD3 zeta chain
The deposited structure of PDB entry 8es7 contains 2 copies of Pfam domain PF11628 (T-cell surface glycoprotein CD3 zeta chain) in T-cell surface glycoprotein CD3 zeta chain. Showing 1 copy in chain A [auth Z].

PF16681
Domain description: Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain
Occurring in:
  1. T-cell surface glycoprotein CD3 epsilon chain
The deposited structure of PDB entry 8es7 contains 2 copies of Pfam domain PF16681 (Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain) in T-cell surface glycoprotein CD3 epsilon chain. Showing 1 copy in chain D [auth F].

PF16680
Domain description: T-cell surface glycoprotein CD3 delta chain
Occurring in:
  1. T-cell surface glycoprotein CD3 delta chain
  2. T-cell surface glycoprotein CD3 gamma chain
The deposited structure of PDB entry 8es7 contains 1 copy of Pfam domain PF16680 (T-cell surface glycoprotein CD3 delta chain ) in T-cell surface glycoprotein CD3 delta chain. Showing 1 copy in chain C [auth D].
The deposited structure of PDB entry 8es7 contains 1 copy of Pfam domain PF16680 (T-cell surface glycoprotein CD3 delta chain ) in T-cell surface glycoprotein CD3 gamma chain. Showing 1 copy in chain E [auth G].

Quick links