8et1

Electron Microscopy
4.48Å resolution

CryoEM structure of GSDMB pore without transmembrane beta-barrel

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo 24-mer (preferred)
PDBe Complex ID:
PDB-CPX-215252 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gasdermin-B Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X
Length: 411 amino acids
Theoretical weight: 46.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8TAX9 (Residues: 1-220, 221-416; Coverage: 98%)
  • Best match: Q8TAX9-1 (Residues: 1-411)
Gene names: GSDMB, GSDML, PP4052, PRO2521
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.48Å
Relevant EMDB volumes: EMD-28583
Expression system: Escherichia coli