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Electron Microscopy
3.41Å resolution

Class2 of the INO80-Nucleosome complex

Released:

Function and Biology Details

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Cellular component:

Structure analysis Details

Assembly composition:
hetero decamer (preferred)
PDBe Complex ID:
PDB-CPX-542821 (preferred)
Entry contents:
6 distinct polypeptide molecules
Macromolecules (6 distinct):
Chromatin-remodeling ATPase INO80 Chain: Q
Molecule details ›
Chain: Q
Length: 1489 amino acids
Theoretical weight: 171.69 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P53115 (Residues: 1-1489; Coverage: 100%)
Gene names: G1880, INO80, YGL150C
Sequence domains:
Actin-related protein 5 Chain: R
Molecule details ›
Chain: R
Length: 755 amino acids
Theoretical weight: 87.68 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P53946 (Residues: 1-755; Coverage: 100%)
Gene names: ARP5, N2430, YNL059C, YNL2430C
Sequence domains: Actin
Chromatin-remodeling complex subunit IES6 Chain: S
Molecule details ›
Chain: S
Length: 166 amino acids
Theoretical weight: 18.56 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P32617 (Residues: 1-166; Coverage: 100%)
Gene names: IES6, SYGP-ORF13, YEL044W
Sequence domains: YL1 nuclear protein C-terminal domain
RuvB-like protein 1 Chains: T, V, X
Molecule details ›
Chains: T, V, X
Length: 463 amino acids
Theoretical weight: 50.52 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: Q03940 (Residues: 1-463; Coverage: 100%)
Gene names: RVB1, TIH1, TIP49A, YDR190C
Sequence domains:
RuvB-like protein 2 Chains: U, W, Y
Molecule details ›
Chains: U, W, Y
Length: 460 amino acids
Theoretical weight: 50.54 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: Q12464 (Residues: 1-460; Coverage: 98%)
Gene names: P1060, RVB2, TIH2, TIP49B, YPL235W
Sequence domains:
Ino eighty subunit 2 Chain: Z
Molecule details ›
Chain: Z
Length: 320 amino acids
Theoretical weight: 36.21 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P40154 (Residues: 1-320; Coverage: 100%)
Gene names: IES2, N1315, YNL215W
Sequence domains: PAPA-1-like conserved region

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.41Å
Relevant EMDB volumes: EMD-28613