› 8euk

X-ray diffraction
1.98Å resolution

cytochrome P450terp (cyp108A1) bound to ethylene glycol

Released:
DOI: 10.2210/pdb8euk/pdb
PDB entry 8euk coloured by chain, front view.
PDB entry 8euk coloured by chain, side view.
PDB entry 8euk coloured by chain, top view.
Source organism: Pseudomonas sp.
Primary publication:
Cooperative Substrate Binding Controls Catalysis in Bacterial Cytochrome P450terp (CYP108A1).
Gable JA, Poulos TL, Follmer AH
J Am Chem Soc (2023)
PMID: 36779970

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152528 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytochrome P450-terp Chain: A
Molecule details ›
Chain: A
Length: 448 amino acids
Theoretical weight: 50.15 KDa
Source organism: Pseudomonas sp.
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P33006 (Residues: 1-428; Coverage: 100%)
Gene names: cyp108, terPC
Sequence domains: Cytochrome P450

Ligands and Environments

2 bound ligands:
Ligand HEM 1 x HEM
Ligand EDO 12 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: P6122
Unit cell:
a: 68.73Å b: 68.73Å c: 457.039Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.181 0.18 0.206
Expression system: Escherichia coli BL21(DE3)

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