› 8ew0

Electron Microscopy
2.7Å resolution

Cryo-EM structure of glutamate dehydrogenase frozen at various temperature

Released:
DOI: 10.2210/pdb8ew0/pdb
PDB entry 8ew0 coloured by chain, front view.
PDB entry 8ew0 coloured by chain, side view.
PDB entry 8ew0 coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Addressing compressive deformation of proteins embedded in crystalline ice.
Shi H, Wu C, Zhang X
Structure (2022)
PMID: 36586403
Related structures: EMD-28639

Function and Biology Details

Reaction catalysed: 
L-glutamate + H(2)O + NAD(P)(+) = 2-oxoglutarate + NH(3) + NAD(P)H
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132441 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutamate dehydrogenase 1, mitochondrial Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 558 amino acids
Theoretical weight: 61.61 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P00366 (Residues: 1-558; Coverage: 100%)
Gene names: GLUD, GLUD1
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.7Å
Relevant EMDB volumes: EMD-28639

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