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Cryo-EM structure of Torpedo nicotinic acetylcholine receptor in complex with etomidate, desensitized-like state

Source organism: Tetronarce californica
Biochemical function: acetylcholine-gated monoatomic cation-selective channel activity
Biological process: excitatory postsynaptic potential
Cellular component: postsynaptic membrane

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF02932
Domain description: Neurotransmitter-gated ion-channel transmembrane region
Occurring in:
  1. Acetylcholine receptor subunit alpha
  2. Acetylcholine receptor subunit delta
  3. Acetylcholine receptor subunit beta
  4. Acetylcholine receptor subunit gamma
The deposited structure of PDB entry 8f6y contains 2 copies of Pfam domain PF02932 (Neurotransmitter-gated ion-channel transmembrane region) in Acetylcholine receptor subunit alpha. Showing 1 copy in chain D.
The deposited structure of PDB entry 8f6y contains 1 copy of Pfam domain PF02932 (Neurotransmitter-gated ion-channel transmembrane region) in Acetylcholine receptor subunit delta. Showing 1 copy in chain B.
The deposited structure of PDB entry 8f6y contains 1 copy of Pfam domain PF02932 (Neurotransmitter-gated ion-channel transmembrane region) in Acetylcholine receptor subunit beta. Showing 1 copy in chain C.
The deposited structure of PDB entry 8f6y contains 1 copy of Pfam domain PF02932 (Neurotransmitter-gated ion-channel transmembrane region) in Acetylcholine receptor subunit gamma. Showing 1 copy in chain E.

PF02931
Domain description: Neurotransmitter-gated ion-channel ligand binding domain
Occurring in:
  1. Acetylcholine receptor subunit alpha
  2. Acetylcholine receptor subunit delta
  3. Acetylcholine receptor subunit beta
  4. Acetylcholine receptor subunit gamma
The deposited structure of PDB entry 8f6y contains 2 copies of Pfam domain PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) in Acetylcholine receptor subunit alpha. Showing 1 copy in chain D.
The deposited structure of PDB entry 8f6y contains 1 copy of Pfam domain PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) in Acetylcholine receptor subunit delta. Showing 1 copy in chain B.
The deposited structure of PDB entry 8f6y contains 1 copy of Pfam domain PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) in Acetylcholine receptor subunit beta. Showing 1 copy in chain C.
The deposited structure of PDB entry 8f6y contains 1 copy of Pfam domain PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) in Acetylcholine receptor subunit gamma. Showing 1 copy in chain E.

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