8f7r

Electron Microscopy
3.28Å resolution

Gi bound mu-opioid receptor in complex with endomorphin

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
PDBe Complex ID:
PDB-CPX-273604 (preferred)
Entry contents:
6 distinct polypeptide molecules
Macromolecules (6 distinct):
Mu-type opioid receptor Chains: M, R
Molecule details ›
Chains: M, R
Length: 403 amino acids
Theoretical weight: 45.48 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
endomorphin Chains: P, Q
Molecule details ›
Chains: P, Q
Length: 5 amino acids
Theoretical weight: 610 Da
Source organism: Homo sapiens
Expression system: Not provided
Guanine nucleotide-binding protein G(i) subunit alpha-1 Chains: A, F
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Chain: B
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Chain: C
scFv16 Chain: E

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.28Å
Relevant EMDB volumes: EMD-28908
Expression systems:
  • Spodoptera frugiperda
  • Not provided
  • Escherichia coli