› 8f8r

Electron Microscopy
3.3Å resolution

Cryo-EM structure of the free barbed end of F-actin

Released:
DOI: 10.2210/pdb8f8r/pdb
PDB entry 8f8r coloured by chain, front view.
PDB entry 8f8r coloured by chain, side view.
PDB entry 8f8r coloured by chain, top view.
Source organism: Oryctolagus cuniculus
Primary publication:
Structures of the free and capped ends of the actin filament.
Carman PJ, Barrie KR, Rebowski G, Dominguez R
Science eadg6812 (2023)
PMID: 37228182
Related structures: EMD-28934

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo heptamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-217328 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Actin, alpha skeletal muscle Chains: A, B, C, D, E, F, G
Molecule details ›
Chains: A, B, C, D, E, F, G
Length: 377 amino acids
Theoretical weight: 42.11 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P68135 (Residues: 1-377; Coverage: 100%)
Gene names: ACTA, ACTA1
Sequence domains: Actin

Ligands and Environments

2 bound ligands:
Ligand ADP 7 x ADP
Ligand MG 7 x MG
1 modified residue:
Ligand HIC 7 x HIC

Experiments and Validation Details

Entry percentile scores
Resolution: 3.3Å
Relevant EMDB volumes: EMD-28934

Quick links

Citations

1 review citation

Mechanisms of actin disassembly and turnover.
Goode et al. (2023)
5 other articles