Function and Biology

Alpha1/BetaB Heteromeric Glycine Receptor in 1 mM Glycine 20 uM Ivermectin State

Source organism: Danio rerio

Sequence families

Pfam Protein families (Pfam)
PF02932
Domain description: Neurotransmitter-gated ion-channel transmembrane region
Occurring in:
  1. Glycine receptor subunit alphaZ1
  2. Glycine receptor, beta b
The deposited structure of PDB entry 8fe1 contains 4 copies of Pfam domain PF02932 (Neurotransmitter-gated ion-channel transmembrane region) in Glycine receptor subunit alphaZ1. Showing 1 copy in chain C.
The deposited structure of PDB entry 8fe1 contains 1 copy of Pfam domain PF02932 (Neurotransmitter-gated ion-channel transmembrane region) in Glycine receptor, beta b. Showing 1 copy in chain E.

PF02931
Domain description: Neurotransmitter-gated ion-channel ligand binding domain
Occurring in:
  1. Glycine receptor subunit alphaZ1
  2. Glycine receptor, beta b
The deposited structure of PDB entry 8fe1 contains 4 copies of Pfam domain PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) in Glycine receptor subunit alphaZ1. Showing 1 copy in chain C.
The deposited structure of PDB entry 8fe1 contains 1 copy of Pfam domain PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) in Glycine receptor, beta b. Showing 1 copy in chain E.

InterPro InterPro annotations
IPR006201
Domain description: Neurotransmitter-gated ion-channel
Occurring in:
  1. Glycine receptor subunit alphaZ1
  2. Glycine receptor, beta b
IPR006028
Domain description: Gamma-aminobutyric acid A receptor/Glycine receptor alpha
Occurring in:
  1. Glycine receptor subunit alphaZ1
IPR008127
Domain description: Glycine receptor alpha
Occurring in:
  1. Glycine receptor subunit alphaZ1
IPR008128
Domain description: Glycine receptor alpha1
Occurring in:
  1. Glycine receptor subunit alphaZ1
IPR036734
Domain description: Neurotransmitter-gated ion-channel ligand-binding domain superfamily
Occurring in:
  1. Glycine receptor subunit alphaZ1
  2. Glycine receptor, beta b
IPR006029
Domain description: Neurotransmitter-gated ion-channel transmembrane domain
Occurring in:
  1. Glycine receptor subunit alphaZ1
  2. Glycine receptor, beta b
IPR036719
Domain description: Neurotransmitter-gated ion-channel transmembrane domain superfamily
Occurring in:
  1. Glycine receptor subunit alphaZ1
  2. Glycine receptor, beta b
IPR038050
Domain description: Neuronal acetylcholine receptor
Occurring in:
  1. Glycine receptor subunit alphaZ1
  2. Glycine receptor, beta b
IPR018000
Domain description: Neurotransmitter-gated ion-channel, conserved site
Occurring in:
  1. Glycine receptor subunit alphaZ1
  2. Glycine receptor, beta b
IPR006202
Domain description: Neurotransmitter-gated ion-channel ligand-binding domain
Occurring in:
  1. Glycine receptor subunit alphaZ1
  2. Glycine receptor, beta b
IPR008060
Domain description: Glycine receptor beta
Occurring in:
  1. Glycine receptor, beta b
IPR047029
Domain description: Glycine receptor subunit beta, transmembrane domain
Occurring in:
  1. Glycine receptor, beta b