8fg1

Solution NMR

Human diaphanous inhibitory domain bound to diaphanous autoregulatory domain

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-271775 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protein diaphanous homolog 1 Chain: A
Molecule details ›
Chain: A
Length: 256 amino acids
Theoretical weight: 29.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O60610 (Residues: 142-380; Coverage: 19%)
Gene names: DIAP1, DIAPH1
Sequence domains:
Protein diaphanous homolog 1 Chain: B
Molecule details ›
Chain: B
Length: 29 amino acids
Theoretical weight: 3.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O60610 (Residues: 1194-1222; Coverage: 2%)
Gene names: DIAP1, DIAPH1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 64%
Refinement method: molecular dynamics
Expression system: Escherichia coli