EC 3.6.4.13: RNA helicase
Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Systematic name:
ATP phosphohydrolase (RNA helix unwinding)
Alternative Name(s):
- CSFV NS3 helicase
- DBP2
- DDX17
- DDX25
- DDX3
- DDX3X
- DDX3Y
- DDX4
- DDX5
- DEAD-box RNA helicase
- DEAD-box protein DED1
- DEAH-box RNA helicase
- DEAH-box protein 2
- DED1
- DbpA
- Dex(H/D) RNA helicase
- EIF4A helicase
- EhDEAD1
- EhDEAD1 RNA helicase
- GRTH/DDX25
- KOKV helicase
- Mtr4p
- NPH-II
- Nonstructural protein 3 helicase
- RHA
- RNA helicase A
- RNA helicase DDX3
- RNA helicase Hera
- RNA-dependent ATPase
- TGBp1 NTPase/helicase domain
- VRH1
EC 2.7.7.50: mRNA guanylyltransferase
Reaction catalysed:
GTP + a 5'-diphospho-[mRNA] = diphosphate + a 5'-(5'-triphosphoguanosine)-[mRNA]
Systematic name:
GTP:mRNA guanylyltransferase
Alternative Name(s):
- GTP--RNA guanylyltransferase
- Messenger RNA guanylyltransferase
- Protein lambda-2
- mRNA capping enzyme
EC 2.1.1.56: mRNA (guanine-N(7))-methyltransferase
Reaction catalysed:
S-adenosyl-L-methionine + a 5'-(5'-triphosphoguanosine)-[mRNA] = S-adenosyl-L-homocysteine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA]
Systematic name:
S-adenosyl-L-methionine:mRNA (guanine-N(7))-methyltransferase
Alternative Name(s):
- Guanine-7-methyltransferase
- Messenger RNA guanine 7-methyltransferase
- Messenger ribonucleate guanine 7-methyltransferase
- S-adenosyl-L-methionine:mRNA (guanine-7-N)-methyltransferase
EC 2.7.7.48: RNA-directed RNA polymerase
Reaction catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Systematic name:
Nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)
Alternative Name(s):
- 3D polymerase
- PB1 proteins
- PB2 proteins
- Phage f2 replicase
- Polymerase L
- Q-beta replicase
- RDRP
- RNA nucleotidyltransferase (RNA-directed)
- RNA replicase
- RNA synthetase
- RNA transcriptase
- RNA-dependent RNA polymerase
- RNA-dependent RNA replicase
- RNA-dependent ribonucleate nucleotidyltransferase
- Ribonucleic acid replicase
- Ribonucleic acid-dependent ribonucleate nucleotidyltransferase
- Ribonucleic acid-dependent ribonucleic acid polymerase
- Ribonucleic replicase
- Ribonucleic synthetase
- Transcriptase
GO terms
Biochemical function:
Biological process:
Cellular component:
Sequence families
Protein families (Pfam)
PF21066
Domain description:
Reovirus core-spike protein lambda-2 (L2), methyltransferase-2
Occurring in:
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>8fjl</span> contains 5 copies of Pfam domain <span class='highlight'>PF21066 (Reovirus core-spike protein lambda-2 (L2), methyltransferase-2)</span> in <span class='highlight'>Outer capsid protein VP1</span>. Showing 1 copy in chain <span class='highlight'>Y</span>. The deposited structure of PDB entry 8fjl contains 5 copies of Pfam domain PF21066 (Reovirus core-spike protein lambda-2 (L2), methyltransferase-2) in Outer capsid protein VP1. Showing 1 copy in chain Y.](https://www.ebi.ac.uk/pdbe/static/entry/8fjl_10_Y_Pfam_PF21066_image-200x200.png)
PF21062
Domain description:
Reovirus core-spike protein lambda-2 (L2), ferredoxin-like domain
Occurring in:
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>8fjl</span> contains 5 copies of Pfam domain <span class='highlight'>PF21062 (Reovirus core-spike protein lambda-2 (L2), ferredoxin-like domain)</span> in <span class='highlight'>Outer capsid protein VP1</span>. Showing 1 copy in chain <span class='highlight'>Y</span>. The deposited structure of PDB entry 8fjl contains 5 copies of Pfam domain PF21062 (Reovirus core-spike protein lambda-2 (L2), ferredoxin-like domain) in Outer capsid protein VP1. Showing 1 copy in chain Y.](https://www.ebi.ac.uk/pdbe/static/entry/8fjl_10_Y_Pfam_PF21062_image-200x200.png)
PF21065
Domain description:
Reovirus core-spike protein lambda-2 (L2), methyltransferase-1
Occurring in:
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>8fjl</span> contains 5 copies of Pfam domain <span class='highlight'>PF21065 (Reovirus core-spike protein lambda-2 (L2), methyltransferase-1)</span> in <span class='highlight'>Outer capsid protein VP1</span>. Showing 1 copy in chain <span class='highlight'>Y</span>. The deposited structure of PDB entry 8fjl contains 5 copies of Pfam domain PF21065 (Reovirus core-spike protein lambda-2 (L2), methyltransferase-1) in Outer capsid protein VP1. Showing 1 copy in chain Y.](https://www.ebi.ac.uk/pdbe/static/entry/8fjl_10_Y_Pfam_PF21065_image-200x200.png)
InterPro annotations
IPR029063
Domain description:
S-adenosyl-L-methionine-dependent methyltransferase superfamily
Occurring in:
Occurring in: