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Golden Shiner Reovirus Core Tropical Vertex

Source organism: Golden shiner reovirus
Biochemical function: ATP binding
Biological process: 7-methylguanosine mRNA capping
Cellular component: viral capsid

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EC 3.6.4.13: RNA helicase

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Systematic name:
ATP phosphohydrolase (RNA helix unwinding)
Alternative Name(s):
  • CSFV NS3 helicase
  • DBP2
  • DDX17
  • DDX25
  • DDX3
  • DDX3X
  • DDX3Y
  • DDX4
  • DDX5
  • DEAD-box RNA helicase
  • DEAD-box protein DED1
  • DEAH-box RNA helicase
  • DEAH-box protein 2
  • DED1
  • DbpA
  • Dex(H/D) RNA helicase
  • EIF4A helicase
  • EhDEAD1
  • EhDEAD1 RNA helicase
  • GRTH/DDX25
  • KOKV helicase
  • Mtr4p
  • NPH-II
  • Nonstructural protein 3 helicase
  • RHA
  • RNA helicase A
  • RNA helicase DDX3
  • RNA helicase Hera
  • RNA-dependent ATPase
  • TGBp1 NTPase/helicase domain
  • VRH1

EC 2.7.7.50: mRNA guanylyltransferase

Reaction catalysed:
GTP + a 5'-diphospho-[mRNA] = diphosphate + a 5'-(5'-triphosphoguanosine)-[mRNA]
Systematic name:
GTP:mRNA guanylyltransferase
Alternative Name(s):
  • GTP--RNA guanylyltransferase
  • Messenger RNA guanylyltransferase
  • Protein lambda-2
  • mRNA capping enzyme

EC 2.1.1.56: mRNA (guanine-N(7))-methyltransferase

Reaction catalysed:
S-adenosyl-L-methionine + a 5'-(5'-triphosphoguanosine)-[mRNA] = S-adenosyl-L-homocysteine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA]
Systematic name:
S-adenosyl-L-methionine:mRNA (guanine-N(7))-methyltransferase
Alternative Name(s):
  • Guanine-7-methyltransferase
  • Messenger RNA guanine 7-methyltransferase
  • Messenger ribonucleate guanine 7-methyltransferase
  • S-adenosyl-L-methionine:mRNA (guanine-7-N)-methyltransferase

EC 2.7.7.48: RNA-directed RNA polymerase

Reaction catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Systematic name:
Nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)
Alternative Name(s):
  • 3D polymerase
  • PB1 proteins
  • PB2 proteins
  • Phage f2 replicase
  • Polymerase L
  • Q-beta replicase
  • RDRP
  • RNA nucleotidyltransferase (RNA-directed)
  • RNA replicase
  • RNA synthetase
  • RNA transcriptase
  • RNA-dependent RNA polymerase
  • RNA-dependent RNA replicase
  • RNA-dependent ribonucleate nucleotidyltransferase
  • Ribonucleic acid replicase
  • Ribonucleic acid-dependent ribonucleate nucleotidyltransferase
  • Ribonucleic acid-dependent ribonucleic acid polymerase
  • Ribonucleic replicase
  • Ribonucleic synthetase
  • Transcriptase

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF03084
Domain description: Reoviral Sigma1/Sigma2 family
Occurring in:
  1. Clamp protein VP6
The deposited structure of PDB entry 8fjl contains 10 copies of Pfam domain PF03084 (Reoviral Sigma1/Sigma2 family) in Clamp protein VP6. Showing 1 copy in chain V.

PF22033
Domain description: Inner capsid protein lambda-1/VP3
Occurring in:
  1. Major inner capsid protein VP3
The deposited structure of PDB entry 8fjl contains 10 copies of Pfam domain PF22033 (Inner capsid protein lambda-1/VP3) in Major inner capsid protein VP3. Showing 1 copy in chain L.

PF13912
Domain description: C2H2-type zinc finger
Occurring in:
  1. Major inner capsid protein VP3
The deposited structure of PDB entry 8fjl contains 10 copies of Pfam domain PF13912 (C2H2-type zinc finger) in Major inner capsid protein VP3. Showing 1 copy in chain L.

PF06016
Domain description: Reovirus core-spike protein lambda-2 (L2), C-terminal
Occurring in:
  1. Outer capsid protein VP1
The deposited structure of PDB entry 8fjl contains 5 copies of Pfam domain PF06016 (Reovirus core-spike protein lambda-2 (L2), C-terminal) in Outer capsid protein VP1. Showing 1 copy in chain Y.

PF21061
Domain description: Reovirus core-spike protein lambda-2 (L2), 7th domain
Occurring in:
  1. Outer capsid protein VP1
The deposited structure of PDB entry 8fjl contains 5 copies of Pfam domain PF21061 (Reovirus core-spike protein lambda-2 (L2), 7th domain) in Outer capsid protein VP1. Showing 1 copy in chain Y.

PF21060
Domain description: Reovirus core-spike protein lambda-2 (L2), 6th domain
Occurring in:
  1. Outer capsid protein VP1
The deposited structure of PDB entry 8fjl contains 5 copies of Pfam domain PF21060 (Reovirus core-spike protein lambda-2 (L2), 6th domain) in Outer capsid protein VP1. Showing 1 copy in chain Y.

PF21066
Domain description: Reovirus core-spike protein lambda-2 (L2), methyltransferase-2
Occurring in:
  1. Outer capsid protein VP1
The deposited structure of PDB entry 8fjl contains 5 copies of Pfam domain PF21066 (Reovirus core-spike protein lambda-2 (L2), methyltransferase-2) in Outer capsid protein VP1. Showing 1 copy in chain Y.

PF21062
Domain description: Reovirus core-spike protein lambda-2 (L2), ferredoxin-like domain
Occurring in:
  1. Outer capsid protein VP1
The deposited structure of PDB entry 8fjl contains 5 copies of Pfam domain PF21062 (Reovirus core-spike protein lambda-2 (L2), ferredoxin-like domain) in Outer capsid protein VP1. Showing 1 copy in chain Y.

PF21065
Domain description: Reovirus core-spike protein lambda-2 (L2), methyltransferase-1
Occurring in:
  1. Outer capsid protein VP1
The deposited structure of PDB entry 8fjl contains 5 copies of Pfam domain PF21065 (Reovirus core-spike protein lambda-2 (L2), methyltransferase-1) in Outer capsid protein VP1. Showing 1 copy in chain Y.

PF21063
Domain description: Reovirus core-spike protein lambda-2 (L2), GTase domain
Occurring in:
  1. Outer capsid protein VP1
The deposited structure of PDB entry 8fjl contains 5 copies of Pfam domain PF21063 (Reovirus core-spike protein lambda-2 (L2), GTase domain) in Outer capsid protein VP1. Showing 1 copy in chain Y.

PF21064
Domain description: Reovirus core-spike protein lambda-2 (L2), N-terminal
Occurring in:
  1. Outer capsid protein VP1
The deposited structure of PDB entry 8fjl contains 5 copies of Pfam domain PF21064 (Reovirus core-spike protein lambda-2 (L2), N-terminal) in Outer capsid protein VP1. Showing 1 copy in chain Y.

PF07781
Domain description: Reovirus minor core protein Mu-2
Occurring in:
  1. Microtubule-associated protein VP5
The deposited structure of PDB entry 8fjl contains 1 copy of Pfam domain PF07781 (Reovirus minor core protein Mu-2) in Microtubule-associated protein VP5. Showing 1 copy in chain B.

PF07925
Domain description: Reovirus RNA-dependent RNA polymerase lambda 3
Occurring in:
  1. RNA-directed RNA polymerase VP2
The deposited structure of PDB entry 8fjl contains 1 copy of Pfam domain PF07925 (Reovirus RNA-dependent RNA polymerase lambda 3) in RNA-directed RNA polymerase VP2. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR013087
Domain description: Zinc finger C2H2-type
Occurring in:
  1. Major inner capsid protein VP3
IPR004317
Domain description: Sigma1/sigma2, reoviral
Occurring in:
  1. Clamp protein VP6
IPR044949
Domain description: Inner capsid protein lambda-1/ VP3 superfamily
Occurring in:
  1. Major inner capsid protein VP3
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. Outer capsid protein VP1
IPR029063
Domain description: S-adenosyl-L-methionine-dependent methyltransferase superfamily
Occurring in:
  1. Outer capsid protein VP1
IPR010311
Domain description: Reovirus core-spike lambda-2
Occurring in:
  1. Outer capsid protein VP1
IPR012494
Domain description: Reovirus minor core protein, Mu-2
Occurring in:
  1. Microtubule-associated protein VP5
IPR007097
Domain description: RNA-directed RNA polymerase, reovirus
Occurring in:
  1. RNA-directed RNA polymerase VP2
IPR043502
Domain description: DNA/RNA polymerase superfamily
Occurring in:
  1. RNA-directed RNA polymerase VP2
IPR012915
Domain description: Reovirus RNA-dependent RNA polymerase lambda 3
Occurring in:
  1. RNA-directed RNA polymerase VP2

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