8fmj

X-ray diffraction
1.33Å resolution

Crystal structure of human KRAS in space group R32

Released:
Model geometry
Fit model/data

Function and Biology Details

Reaction catalysed:
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-133991 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
GTPase KRas, N-terminally processed Chain: A
Molecule details ›
Chain: A
Length: 176 amino acids
Theoretical weight: 20.27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P01116 (Residues: 1-169; Coverage: 89%)
  • Best match: P01116-2 (Residues: 1-169)
Gene names: KRAS, KRAS2, RASK2
Sequence domains: Ras family

Ligands and Environments

No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: R32
Unit cell:
a: 92.516Å b: 92.516Å c: 117.775Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.143 0.142 0.166
Expression system: Escherichia coli BL21(DE3)